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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHA2
All Species:
27.27
Human Site:
T422
Identified Species:
66.67
UniProt:
Q86XE3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XE3
NP_859074.1
530
60711
T422
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Chimpanzee
Pan troglodytes
XP_519613
530
60695
T422
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Rhesus Macaque
Macaca mulatta
XP_001094797
530
60679
T422
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Dog
Lupus familis
XP_848512
537
61387
T429
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CTY5
523
59792
T415
I
S
E
E
K
G
I
T
F
D
E
F
R
S
F
Rat
Rattus norvegicus
Q99P63
432
49423
A331
H
L
E
D
F
A
I
A
M
Q
T
F
S
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420691
752
84225
T644
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Frog
Xenopus laevis
NP_001090059
430
49121
T329
N
L
E
D
F
S
I
T
M
K
M
F
S
S
A
Zebra Danio
Brachydanio rerio
A4IG32
489
55907
T372
F
K
D
A
Q
G
I
T
F
E
E
V
E
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392106
461
54367
F360
T
F
E
E
F
R
R
F
Y
Q
F
L
N
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96
90.5
N.A.
91.5
37.9
N.A.
N.A.
55.9
39.2
20.5
N.A.
N.A.
41.1
N.A.
N.A.
Protein Similarity:
100
99.8
96.5
92.3
N.A.
93.5
53.7
N.A.
N.A.
62.3
55.6
38.6
N.A.
N.A.
56.2
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
20
N.A.
N.A.
100
33.3
40
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
100
40
66.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
20
0
0
0
0
0
60
0
0
0
0
0
% D
% Glu:
0
0
90
70
0
0
0
0
0
10
70
0
10
0
0
% E
% Phe:
10
10
0
0
30
0
0
10
70
0
10
80
0
0
70
% F
% Gly:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
0
0
90
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
60
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
20
0
0
0
0
0
0
0
0
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
20
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
10
20
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
0
0
0
0
60
0
0
% R
% Ser:
0
10
0
0
0
10
0
0
0
0
0
0
20
70
0
% S
% Thr:
10
0
0
0
0
0
0
80
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _